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Pediatric Clinical Trials

haley and dr irwin

Bone

AEWS1221

Randomized Phase 2 Trial Evaluating the Addition of the IGF-1R Monoclonal Antibody Ganitumab (AMG 479, NSC# 750008) to Multiagent Chemotherapy for Patients With Newly Diagnosed Metastatic Ewing Sarcoma 

Protocol Summary

AEWS1031

A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma 

Protocol Summary

Brain

ACNS0831

Phase III Randomized Trial of Post-Radiation Chemotherapy in Patients With Newly Diagnosed Ependymoma Ages 1 to 21 Years

Protocol Summary

Gastrointestinal

AHEP0731

Treatment of Children With All Stages of Hepatoblastoma With Temsirolimus (NSC#683864) Added to High Risk Stratum Treatment

Protocol Summary

Genitourinary

AREN03B2

Renal Tumors Classification, Biology, and Banking Study

Protocol Summary

Head & Neck

ACNS0332

Efficacy of Carboplatin Administered Concomitantly With Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other Than Average Risk Medulloblastoma/PNET Patients 

Protocol Summary

ACNS1221

A Phase II Study for the Treatment of Non-metastatic Nodular Desmoplastic Medulloblastoma in Children Less Than 4 Years of Age

Protocol Summary

ANBL1232

Utilizing Response- and Biology-Based Risk Factors to Guide Therapy in Patients With Non-high-risk Neuroblastoma

Protocol Summary

Hematology

AALL1131

A Phase III Randomized Trial for Newly Diagnosed High Risk B-Lymphoblastic Leukemia (B-ALL) Testing Clofarabine (NSC# 606869) in the Very High Risk Stratum

Protocol Summary

AALL0932

Treatment of Patients With Newly Diagnosed Standard Risk B-Lymphoblastic Leukemia (B-ALL) or Localized B-Lineage Lymphoblastic Lymphoma (B-LLy)

Protocol Summary

AALL08B1

Classification of Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)

Protocol Summary

AALL05B1

A Children's Oncology Group Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens

Protocol Summary

ACCL0933

A Randomized Open-Label Trial of Caspofungin Versus Fluconazole to Prevent Invasive Fungal Infections in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML)

Protocol Summary

AALL1231

A Phase III Randomized Trial Investigating Bortezomib (NSC# 681239) on a Modified Augmented BFM (ABFM) Backbone in Newly Diagnosed T-Lymphoblastic Leukemia (T-ALL) and T-Lymphoblastic Lymphoma (T-LLy)

Protocol Summary

ANHL12P1

A Randomized Phase II Trial of Brentuximab Vedotin (SGN35, NSC# 749710), or Crizotinib (NSC#749005, Commercially Labeled) in Combination With Chemotherapy for Newly Diagnosed Patients With Anaplastic Large Cell Lymphoma (ALCL) IND # 117117

Protocol Summary

AAML1031

A Phase III Randomized Trial for Patients With De Novo AML Using Bortezomib and Sorafenib (NSC# 681239, NSC# 724772) for Patients With High Allelic Ratio FLT3/ITD

Protocol Summary

Other

APEC14B1

The Project: Every Child Protocol: A Registry, Eligibility Screening, Biology and Outcome Study

Protocol Summary

ALTE05N1

Umbrella Long-Term Follow-Up Protocol

Protocol Summary

ANBL00B1

Neuroblastoma Biology Studies

Protocol Summary

Soft Tissue

D9902

A COG Soft Tissue Sarcoma Diagnosis, Biology and Banking Protocol

Protocol Summary